Resection of hypertrophic papillary muscles and mitral valve replacement in a patient with midventricular hypertrophic obstructive cardiomyopathy – a new approach

Midventricular hypertrophic obstructive cardiomyopathy (HOCM) is characterized by hypertrophy of the interventricular septum (IVS) and – in rare cases – of the papillary muscles (PM), which subsequently can ca…  Read More

Totally endoscopic concomitant aortic and mitral valve surgery in junctional epidermolysis bullosa: a case report

Junctional epidermolysis bullosa is a rare skin and mucosal disorder characterized by blister formation in response to minor trauma and extracutaneous manifestations. There have been no reports of cardiac surg…  Read More

Totally endoscopic concomitant aortic and mitral valve surgery in junctional epidermolysis bullosa: a case report

Junctional epidermolysis bullosa is a rare skin and mucosal disorder characterized by blister formation in response to minor trauma and extracutaneous manifestations. There have been no reports of cardiac surg…  Read More

Staged therapeutic surgery for progressive pulmonary regurgitation and pacemaker induced cardiomyopathy after the tetralogy of fallot repair

Recently, improvements in the repair of tetralogy of Fallot have increased the need for reoperation in adulthood, and it’s not rare that these reoperation candidates suffer from biventricular failure. However,…  Read More

Effect of multi arm-PEG-NHS (polyethylene glycol n-hydroxysuccinimide) branching on cell adhesion to modified decellularized bovine and porcine pericardium

J Mater Chem B. 2024 Jan 31;12(5):1244-1256. doi: 10.1039/d3tb01661g.

ABSTRACT

Implanting physical barrier materials to separate wounds from their surroundings is a promising strategy for preventing postoperative adhesions. Herein, we develop a material that switches from an anti-adhesive surface to an adhesive surface, preventing adhesion in the early stage of transplantation and then promoting recellularization. In this study, 2-arm, 4-arm, and 8-arm poly(ethylene glycol) succinimidyl glutarate (2-, 4-, 8-arm PEG-NHS) were used to modify the surface of decellularized porcine and bovine pericardium. The number of free amines on the surface of each material significantly decreased following modification regardless of the reaction molar ratio of NH2 and NHS, the number of PEG molecule branches, and the animal species of the decellularized tissue. The structure and mechanical properties of the pericardium were maintained after modification with PEG molecules. The time taken for the PEG molecules to detach through hydrolysis of the ester bonds differed between the samples, which resulted in different cell repulsion periods. By adjusting the reaction molar ratio, the number of PEG molecule branches, and the animal species of the decellularized pericardium, the duration of cell repulsion can be controlled and is expected to provide an anti-adhesion material for a variety of surgical procedures.

PMID:38168715 | DOI:10.1039/d3tb01661g

Femorotibial Bypass Sutured on Bovine Pericardium Patch of the Femoral Artery for Bypass Inflow: A Case Report

Cureus. 2023 Nov 25;15(11):e49381. doi: 10.7759/cureus.49381. eCollection 2023 Nov.

ABSTRACT

A 72-year-old man presented with intermittent claudication and a foot ulcer. Computed tomography revealed severe calcification and occlusion of the left femoral artery and calcification and stenosis from the superficial femoral artery to the popliteal artery. Thromboendarterectomy (TEA) and anterior reconstruction of the femoral artery with a bovine pericardium patch were performed. We sutured the great saphenous vein on the bovine pericardium patch for bypass inflow after creating an anastomosis hole with a puncher and performed an in situ femorotibial bypass. This technique helped us achieve a smooth and clean anastomosis. In situ vein graft anastomosis might be difficult on severely atherosclerotic femoral artery after TEA and difficult anastomosis increases the risk of bypass occlusion. Anastomosis on the bovine pericardium patch for bypass inflow might ensure smooth and clean anastomosis in patients with severe atherosclerosis of the femoral artery.

PMID:38024018 | PMC:PMC10676049 | DOI:10.7759/cureus.49381

Clinical and functional outcomes associated with pulmonary complications after coronary artery bypass grafting

Coronary artery bypass grafting(CABG) is a surgical treatment for coronary artery disease aiming at improving symptoms and life expectancy. Despite this, there are pulmonary and functional complications that m…  Read More

Clinical and functional outcomes associated with pulmonary complications after coronary artery bypass grafting

Coronary artery bypass grafting(CABG) is a surgical treatment for coronary artery disease aiming at improving symptoms and life expectancy. Despite this, there are pulmonary and functional complications that m…  Read More