Left ventricular noncompaction cardiomyopathy (LVNC) is a rare myocardial developmental anomaly characterized by incomplete myocardial compact layer development in the left ventricular wall, resulting in a mul… Read More
Category: General
The combination of chemotherapy and immune checkpoint inhibitors in recurrent extensive-stage small cell lung cancer: a case report
Small cell lung cancer (SCLC) accounts for approximately 15% of all lung cancer cases and is characterized by high malignancy, rapid progression, and poor prognosis. Here, we report a case of a 58-year-old fem… Read More
Intermittent mitral prosthetic dysfunction. what interferes the valve closure?
Prosthetic valve dysfunction due to entrapment of the subvalvular apparatus is a rare condition, particularly when occurring as a delayed postoperative complication. Spontaneous papillary muscle rupture in the… Read More
Complex management of ectopia cordis complicated by pentalogy of cantrell: Report of two cases and review of current evidence
Int J Surg Case Rep. 2025 Jun;131:111353. doi: 10.1016/j.ijscr.2025.111353. Epub 2025 Apr 23.
ABSTRACT
INTRODUCTION AND IMPORTANCE: Ectopia cordis is a rare congenital anomaly characterized by the abnormal positioning of the heart outside the thoracic cavity, frequently associated with additional congenital defects such as those seen in Pentalogy of Cantrell. Due to the rarity and severity of these anomalies, timely diagnosis and appropriate management remain clinically challenging but critical for patient outcomes.
CASE PRESENTATION: We report two distinct cases of ectopia cordis managed at our institution. The first case presented with complete ectopia cordis and absence of the sternum, requiring initial management with a Bogota bag followed by placement of bovine pericardium; unfortunately, the patient succumbed to complications of sepsis and heart failure at 12 days of life. The second case involved partial ectopia cordis accompanied by features of Pentalogy of Cantrell, managed conservatively with a Bogota bag and spontaneous epithelialization, resulting in successful discharge with stable clinical status.
CLINICAL DISCUSSION: Management of ectopia cordis, especially when complicated by associated anomalies, presents significant surgical and clinical challenges. Survival rates remain low due to complications such as sepsis, cardiac instability, and limited thoracic cavity space. Utilization of biomaterials like bovine pericardium has shown promise in providing necessary cardiac protection when primary closure is not feasible. Early multidisciplinary intervention, involving neonatologists, pediatric cardiologists, and surgeons, is crucial for optimizing outcomes.
CONCLUSION: While prognosis for ectopia cordis remains poor, careful and individualized management strategies, including timely intervention and infection prevention, can lead to favorable outcomes as demonstrated in our second case. This underscores the importance of a multidisciplinary approach and early prenatal diagnosis in enhancing survival rates for this rare condition.
PMID:40286694 | PMC:PMC12059706 | DOI:10.1016/j.ijscr.2025.111353
Intermittent mitral prosthetic dysfunction. what interferes the valve closure?
Prosthetic valve dysfunction due to entrapment of the subvalvular apparatus is a rare condition, particularly when occurring as a delayed postoperative complication. Spontaneous papillary muscle rupture in the… Read More
Exploring the relationship between ankle strength and endurance factors and the severity and level of ischemia in patients with peripheral arterial disease
Peripheral Arterial Disease (PAD) is a global health concern, particularly among aging populations. While previous studies have examined various aspects of PAD, the role of ankle muscle strength and endurance … Read More
Successful management of cardiac electrical storm after aortic valve replacement using stellate ganglion block: a case report
Cardiac electrical storm (CES) is a life-threatening state of electrical instability characterized by 3 or more episodes of sustained ventricular arrhythmia within 24 h. The application of stellate ganglion bl… Read More
Exploring the relationship between ankle strength and endurance factors and the severity and level of ischemia in patients with peripheral arterial disease
Peripheral Arterial Disease (PAD) is a global health concern, particularly among aging populations. While previous studies have examined various aspects of PAD, the role of ankle muscle strength and endurance … Read More
Superselective transcatheter arterial embolization in the treatment of intra-abdominal extralobar pulmonary sequestration
Radiol Case Rep. 2025 Apr 5;20(6):3111-3115. doi: 10.1016/j.radcr.2025.03.019. eCollection 2025 Jun.
ABSTRACT
Pulmonary sequestration is a congenital anomaly characterized by a mass of nonfunctioning lung parenchyma that receives a systemic arterial blood supply and is mainly located in the thorax. Intra-abdominal pulmonary sequestration, a rare subtype, is typically diagnosed within the first few months of life. We report the case of a term neonate with a history of recurrent left-sided pleural effusion requiring thoracentesis. A CT scan with venous contrast was performed, and an intrabdominal extralobar pulmonary sequestration was identified on the left, associated with a diaphragmatic hernia. The patient underwent embolization of the anomalous branch and reconstruction of the left diaphragm using bovine pericardium.
PMID:40242385 | PMC:PMC12002766 | DOI:10.1016/j.radcr.2025.03.019
Effects of cilostazol for in-stent restenosis after carotid artery stenting: a meta-analysis
There is some controversy regarding drug therapy to prevent in-stent restenosis (ISR) after carotid artery stenting. In recent years, cilostazol has received increasing research attention. We performed a meta-… Read More