Primary cardiac lymphoma (PCL) is a rare malignancy, representing a small fraction of primary cardiac tumors. Non-germinal center B-cell (non-GCB) diffuse large B-cell lymphoma (DLBCL), a subtype of PCL, often… Read More
Category: General
Innovative strategies in coagulation management for cardiothoracic surgery: a narrative review of pharmacological and nonpharmacological approaches
The challenging management of coagulation in cardiothoracic surgery requires a multifaceted approach. The use of pharmacological interventions such as tranexamic acid, heparin, and aprotinin minimizes bleeding… Read More
Utilization of Bovine Pericardium Patch During Common Femoral Endarterectomy
J Clin Med. 2025 May 30;14(11):3852. doi: 10.3390/jcm14113852.
ABSTRACT
Background/Objectives: Common femoral endarterectomy (CFE) is one of the most frequent open arterial surgical procedures. The ideal material to close the arteriotomy is equivocal. This study aims to evaluate the efficacy and safety of bovine pericardium patch (BPP) utilization in femoral artery bifurcation endarterectomy (FE). Methods: A single-center, retrospective study was conducted, involving 200 consecutive FE procedures performed between November 2019 and December 2022. Clinical data, including demographics, comorbidities, surgical details, and outcomes, were collected from institutional records. The primary endpoints were overall survival, reintervention-free survival, and amputation-free survival. Secondary endpoints included the incidence of surgical site infection (SSI) and its associated risk factors. Logistic regression models were used to identify predictors of SSI, adjusting for confounders such as age, smoking, comorbidities, and bacterial colonization. Results: The median age of the cohort was 68 (SD ± 9.70) years, and 66% were male. The median follow-up period was 1010 (SD ± 471.47) days. Thirty-day survival was 91%, and 2 year survival was 69.3%, with cardiovascular events and cancer being the leading causes of death. Reintervention-free survival was 94.7% at 30 days and 77.5% at 2 years, while amputation-free survival was 94.3% at 30 days and 87.4% at 2 years. SSI requiring surgery occurred in 16% of patients, with a higher risk observed in patients with critical limb ischemia (CLI) compared to those with claudication. The presence of pathogens such as MRSA, Escherichia coli, and Pseudomonas aeruginosa (OR 16.1, p < 0.001) was significantly associated with SSI. Previous groin surgery did not affect SSI incidence. Conclusions: BPP utilization in FE provides favorable patency and survival outcomes, even in a high-risk patient population with significant comorbidities. CLI and bacterial colonization increased the risk of SSI. Perioperative infection prevention strategies and management of systemic comorbidities are essential to improve patient outcomes.
PMID:40507613 | PMC:PMC12156278 | DOI:10.3390/jcm14113852
Elevated tumour markers in the pleural effusion of a patient with spontaneous esophageal rupture: a rare case report
Esophageal rupture is a rare but life-threatening condition. Esophageal tumours do not usually cause esophageal ruptures, and elevated tumour markers have rarely been detected in pleural effusion after esophag… Read More
Clinical significance of lncRNA PAX8-AS1 and miR-96-5p in non-small cell lung cancer
This study aims to examine the potential value of lncRNA PAX8-AS1 and miR-96-5p as diagnostic markers in non-small cell lung cancer (NSCLC). The goal is to provide a reference for improving adverse outcomes in… Read More
The role of thoracic surgeons in spinal surgery: our clinical experiences
In the thoracic area, the outside edge of the vertebrae exhibits intricate anatomical features. A multidisciplinary approach is necessary, particularly in scoliosis surgery, while performing manipulations on t… Read More
Identification of potential drug targets for achalasia from genetic insights: a Mendelian randomization study
Achalasia (AC) is an esophageal dyskinetic disorder characterized by loss of function of ganglion cells of the intermuscular plexus of the distal esophagus and lower esophageal sphincter. Although there have b… Read More
Nicorandil in improving angina pectoris and vascular endothelial function in elderly diabetes mellitus patients with coronary heart disease
To explore the clinical efficacy of nicorandil in treating elderly angina pectoris with diabetes mellitus (DM) and coronary heart disease (CHD), and the effect on improving vascular endothelial function (VEF).
Cardiac calcified amorphous tumor in the right atrium: a rare cardiac neoplasm
Cardiac calcified amorphous tumors (CATs) represent rare, nonneoplastic intraluminal heart masses, with limited case reports in existing literature. Asymptomatic cases localized in the right atrium are particu… Read More
[MEP-41] Management of Diaphgramatic Dehiscence and Wound Infection After Open Repair of Thoracoabdominal Aortic Aneurysm
Turk Gogus Kalp Damar Cerrahisi Derg. 2024 Dec 31;32(4 Suppl 2):138-139. doi: 10.5606/tgkdc.dergisi.2024.mep-41. eCollection 2024 Nov.
ABSTRACT
Herein, we presented a case of thoracoabdominal aneurysm that was surgically treated and was complicated with diaphragmatic dehiscence and wound infection. Management and treatment methods of this challenging complication were discussed. A 59-year-old male patient with a history of renal operation underwent an open surgical treatment for thoracoabdominal aortic aneurysm. After extubation, the chest radiograph revealed left pneumothorax, and diaphragmatic dehiscence was detected on computed tomography. In the reoperation, steel wires attaching to the arcus costarum were broken off, and the diaphragmatic dehiscence and eventration of organs were observed. Diaphragmatic defect was closed with a Dacron patch, as it was very large for primary closure. Chylothorax was noticed and treated by somatostatin infusion. Vacuum therapy was applied as a purulent discharge started, and necrotic tissue was observed with evidence of infection when debridement was performed. Antibiotic therapy was started according to antibiogram. Vacuum therapy of thoracal incision was stopped as granulation tissue was observed, and the wound was closed by retention sutures. The wound in the abdominal region was closed with an advancement flap by subcutaneous detachment by plastic surgery, and a hemovac drain was placed. Since purulent discharge persisted, the Dacron graft was replaced by bovine pericardium for the diaphragmatic defect. The wound in the abdominal region was closed with retention sutures. The skin was closed primarily. When the infection resolved, the patient was discharged with peroral antibiotics. In open surgical repair of thoracoabdominal aortic aneurysm, rapid diagnosis and surgical intervention in case of diaphragm dehiscence, closure of the wound with appropriate treatment methods, reduction of the wound size with vacuum assisted closure, and initiation of effective antibiotic therapy by taking serial cultures are important in the treatment process.
PMID:40322089 | PMC:PMC12045207 | DOI:10.5606/tgkdc.dergisi.2024.mep-41