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Initial experience of using the Invengenx® bovine pericardial tissue patch for common arterial trunk repair

Engineered heterografts like bovine pericardial tissue patches are often fashioned into conduits for repairs of complex congenital cardiac defects such as truncus arteriosus (BPTP). Choosing the right graft that has suitable mechanical properties, durability, antigenicity and availability in the right size and shape is a difficult task. We report our initial experience with the new Invengenx® BPTP that is crosslinked using proprietary fixation methodology called elixP™ in a 6-month-old patient with a type 2 TA on whom we performed a truncus repair, closure of ventricular septal defect (VSD) and right ventricular outflow tract (RVOT) reconstruction. A size XM-12 (2×9 cm) Invengenx® BPTP was hand-sewn to prepare a conduit. Distal anastomosis was done between the conduit and the PA confluence. The conduit could be hand-sewn with ease, had optimal thickness and strength and showed good performance as seen on post-operative echocardiography.

Shah, P., T. Dudde, S. Kamath, K. Surya, K. V. Bilgi, and R. Kupumbati. “Initial Experience of Using the Invengenx® Bovine Pericardial Tissue Patch for Common Arterial Trunk Repair”. International Journal of Research in Medical Sciences, vol. 12, no. 7, June 2024, pp. 2722-3, doi:10.18203/2320-6012.ijrms20241941.

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