Postoperative stroke is one of the most serious consequences of cardiac surgery. Morbidity risk assessment is critical for preoperative risk assessments and resource allocation. In this article, we aim to inve… Read More
Category: General
Surgical resection of a rare biatrial giant sarcoma: a case report
Primary cardiac undifferentiated sarcoma is an exceptionally rare entity, marked by nonspecific symptoms that considerably challenge its diagnosis and treatment. Surgical resection generally serves as the prim… Read More
Prognostic value of non-invasive right ventricle-pulmonary artery coupling in patients with pulmonary hypertension associated with left heart disease
This study aims to assess the prognostic significance of non-invasive right ventricle-pulmonary artery coupling in patients with pulmonary hypertension associated with left heart disease (PH-LHD) and identify … Read More
Optimizing surgical precision: a comparative study of three-port vs. four-port robotic-assisted lobectomy for NSCLC
In recent years, robot-assisted thoracoscopic surgery has seen major advances. The feasibility and safety of this new surgical procedure have been widely recognized. However, only a few studies have investigat… Read More
Feasibility of postoperative home-based pulmonary function training for lung cancer patients: a real-world study
Pulmonary surgery can significantly impact patients’ respiratory function and reduce their quality of life. Previous studies have shown that perioperative breathing exercises (BE) can facilitate the recovery o… Read More
The importance of tissue science and valve design in relation to durability and hemodynamics of the DurAVR aortic heart valve
Front Cardiovasc Med. 2025 Feb 7;12:1512961. doi: 10.3389/fcvm.2025.1512961. eCollection 2025.
ABSTRACT
INTRODUCTION: Clinical evidence highlighting the efficacy and safety of transcatheter aortic valve replacement (TAVR) and the 2019 Food and Drug Administration (FDA) approval for TAVR in low-risk (younger) patients has created a demand for durable and long-lasting bioprosthetic heart valve (BHV) leaflet materials. Over the life of an implanted BHV mechanical stress, immunogenicity, calcification, and hemodynamic dysfunction lead to failure via structural valve deterioration (SVD). Consequently, the durability of the bioprosthetic materials selected for valve manufacture is of utmost importance.
TECHNOLOGY: The ADAPT™ tissue engineering process, an anti-calcification preparation that transforms xenograft tissue (bovine pericardium) into a durable valve bioscaffold, shows significant clinical benefits in mitigating the interrelated mechanisms leading to SVD. The novel acellular, biostable and non-calcifying biomaterial has recently been molded into a single-piece 3D biomimetic valve (DurAVR™) with excellent early clinical results and the potential to meet the growing demand of durable BHVs for the treatment of aortic stenosis.
DISCUSSION: The unique design of the DurAVR biomimetic valve in combination with the superior biostability of ADAPT tissue could advance the BHV space by providing superior performance and durability to aortic stenosis patients in need of TAVR.
PMID:39991635 | PMC:PMC11842446 | DOI:10.3389/fcvm.2025.1512961
Ketamine as part of multi-modal analgesia may reduce opioid requirements following cardiac surgery: a retrospective observational cohort study
Postoperative pain control in cardiac surgery is often managed with opioid medications. Insufficient analgesia can result in complications including splinting, pneumonia, and delay of appropriate rehabilitatio… Read More
Ketamine as part of multi-modal analgesia may reduce opioid requirements following cardiac surgery: a retrospective observational cohort study
Postoperative pain control in cardiac surgery is often managed with opioid medications. Insufficient analgesia can result in complications including splinting, pneumonia, and delay of appropriate rehabilitatio… Read More
Left ventricular fibromas in pediatric patients: a case series and review of the literature
Cardiac fibromas are rare benign primary tumors of the heart; nearly one-third of affected patients are less than 1 year old, and only 15% of patients develop this disease in adulthood. Here, we report three c… Read More
Real-time blood gas management: evaluating quantum perfusion system’s accuracy against a standard blood gas analysis in CPB
Continuous blood gas monitoring (CBGM) during cardiopulmonary bypass (CPB) is essential for maintaining optimal patient outcomes, enabling rapid responses to critical fluctuations in blood gas parameters. This… Read More