Basic Clin Androl. 2026 Jan 21;36(1):1. doi: 10.1186/s12610-025-00298-7.
ABSTRACT
BACKGROUND: Surgical correction of Peyronie’s disease often requires grafting techniques to restore penile anatomy and function. The bovine pericardial patch is a promising biomaterial due to its strength, elasticity, and biocompatibility. This study evaluates the safety, handling, and clinical outcomes associated with its use in tunical grafting procedures.
METHODS: A prospective, single-centre clinical study enrolled six patients with Peyronie’s disease requiring plaque incision and grafting. Data on surgical handling characteristics, postoperative outcomes, complications, and patient satisfaction were collected and analysed descriptively using standard statistical methods.
RESULTS: All surgeries were completed without intraoperative complications. Patch handling characteristics were rated as excellent across all surgical parameters. No adverse events, graft-related complications, or loss of penile function were observed during the follow-up period. Patient satisfaction was rated as very high at discharge and at one-month follow-up.
CONCLUSIONS: Bovine pericardial tissue patch grafting demonstrated excellent safety, efficacy, and high satisfaction rates for surgical correction of Peyronie’s disease deformities. These findings support its wider clinical application, although larger studies with extended follow-up are warranted to confirm long-term outcomes.
PMID:41566209 | PMC:PMC12821321 | DOI:10.1186/s12610-025-00298-7