Month: July 2025

Radiol Case Rep. 2025 Apr 5;20(6):3111-3115. doi: 10.1016/j.radcr.2025.03.019. eCollection 2025 Jun.

ABSTRACT

Pulmonary sequestration is a congenital anomaly characterized by a mass of nonfunctioning lung parenchyma that receives a systemic arterial blood supply and is mainly located in the thorax. Intra-abdominal pulmonary sequestration, a rare subtype, is typically diagnosed within the first few months of life. We report the case of a term neonate with a history of recurrent left-sided pleural effusion requiring thoracentesis. A CT scan with venous contrast was performed, and an intrabdominal extralobar pulmonary sequestration was identified on the left, associated with a diaphragmatic hernia. The patient underwent embolization of the anomalous branch and reconstruction of the left diaphragm using bovine pericardium.

PMID:40242385 | PMC:PMC12002766 | DOI:10.1016/j.radcr.2025.03.019

Cureus. 2025 Mar 15;17(3):e80621. doi: 10.7759/cureus.80621. eCollection 2025 Mar.

ABSTRACT

Percutaneous coronary intervention is now commonly performed using the transradial artery approach, but endovascular therapy (EVT) is still often performed via the femoral artery (FA). Vascular closure devices have been developed and are commonly used to achieve hemostasis at the FA puncture site. However, there have been some reports of infection complications associated with the use of vascular closure devices. When Perclose ProStyle Suture® (Abbott, Abbott Park, IL, USA) is used for hemostasis in thin patients, the puncture site may become umbilical depressed. We report three cases of umbilical puncture site depression with the Perclose ProStyle Suture®. Case 1 was a 78-year-old male with a body mass index (BMI) of 18 kg/m² and a thin build who underwent EVT for peripheral arterial disease with rest pain. Stents were implanted in the stenosis of both external iliac arteries and the occluded lesion of the right superficial femoral artery (SFA) via the left FA approach. The puncture site was sutured with Perclose ProStyle Suture®, but the puncture site became depressed like a navel. One month later, he visited the hospital with pus discharge from the left FA puncture site, and one week later, he visited the hospital with bleeding from an infected pseudoaneurysm. Although vascular repair surgery was performed, it recurred a month later, and thus the infected tissue was debrided and vascularization was performed using a bovine pericardial patch. Case 2 was an 88-year-old female with a BMI of 18 kg/m² who was thin and had intermittent claudication. EVT was performed on the occluded lesion in the left SFA. A stent was implanted in the left SFA via the right FA, and the puncture site was hemostatized with Perclose ProStyle Suture®. Two weeks later, she was referred to our institution because of bleeding from the puncture site in her right FA, and a contrast computed tomography revealed an infected pseudoaneurysm. She was referred to vascular surgery, where the infected area was debrided and vascular repair surgery was performed. Case 3 was a 72-year-old male (BMI 18.4 kg/m²) with intermittent claudication. EVT was performed for a severe stenosis lesion in the right SFA. A stent was implanted in the right SFA via the left FA approach, and the puncture site was hemostatized using Perclose ProStyle Suture®. The puncture site then became depressed like a navel. Based on the experience of cases 1 and 2, the subcutaneous tissue around the suture was incised, the suture was buried in the subcutaneous tissue, and the dermis was sutured with 5-0 absorbable sutures. The patient is being followed up as an outpatient, and there is no evidence of infection, and the condition is good. Due to the design of the device, the Perclose ProStyle Suture® is designed to suture approximately 1 cm proximal to the vessel wall. Therefore, in such cases, where the patient is thin and has thin subcutaneous tissue, the suture is placed close to the dermis, and when ligated, the dermis is depressed like a navel. When the suture is close to the dermis, the risk of vascular infection increases; therefore, it is preferable to perform the repair so that the suture is buried in the subcutaneous tissue.

PMID:40230772 | PMC:PMC11996046 | DOI:10.7759/cureus.80621

J Nanobiotechnology. 2025 Jul 1;23(1):470. doi: 10.1186/s12951-025-03493-w.

ABSTRACT

BACKGROUND: High myopia (HM) is a progressive ocular condition characterized by excessive axial elongation and severe refractive errors, often leading to sight-threatening complications. The underlying pathological driver of HM is the weakening of scleral biomechanics, making the sclera a key therapeutic target. While posterior scleral reinforcement (PSR) has been established as an effective intervention to strengthen the sclera, currently available PSR materials often fail to fully meet clinical demands.

RESULTS: Inspired by the electric eel, which generates surface electrolytes to facilitate electric discharge and influence interactions with its surroundings, we developed a biomimetic piezoelectric patch (BPP@PVDF) for HM treatment. This patch integrates a bovine pericardium (BPP) scaffold with a piezoelectric polyvinylidene fluoride (PVDF) film, endowing the BPP with electrical properties and improved cell adhesion. Through electrical activation, the BPP enhances scleral mechanical strength and promotes collagen synthesis, effectively mitigating axial elongation in myopia.

CONCLUSIONS: Both in vitro and in vivo experiments demonstrate that our precisely designed patch provided a stable and effective solution for reducing progressive axial elongation in HM. By leveraging nanotechnology, electrical stimulation, and scleral reinforcement surgery, this study offers a groundbreaking approach with significant implications for both scientific research and clinical practice. Our strategy paves the way for enhanced surgical outcomes in HM treatment, offering a promising avenue for future therapeutic advancements.

PMID:40598551 | DOI:10.1186/s12951-025-03493-w

Kyobu Geka. 2025 May;78(5):371-375.

ABSTRACT

Primary angiosarcoma of the heart is extremely rare with poor prognosis. A 39-year-old man presented to his physician for evaluation of fever and pericardial pain and was referred to our department for further management. The patient’s condition stabilized after pericardiocentesis;however, the cause of cardiac tamponade remained undetermined on admission. Transesophageal echocardiography and electrocardiography-synchronized contrast-enhanced computed tomography (CT) revealed a suspected source of bleeding in the right atrium, necessitating open chest surgery. Preoperative imaging showed no evidence of a tumor;however, intraoperatively, we observed a suspected right atrial tumor, which was resected, followed by repair using a bovine pericardial patch. Histopathological examination confirmed diagnosis of angiosarcoma. Angiosarcoma is often diagnostically challenging in the early stages, and multiple examinations are important for early diagnosis and treatment.

PMID:40589042