Tissue engineered decellularized bovine pericardium as prosthetic material in paediatric cardiac surgery

Indian J Thorac Cardiovasc Surg. 2025 Jan;41(1):35-40. doi: 10.1007/s12055-024-01769-8. Epub 2024 Jul 1.

ABSTRACT

AIM: To evaluate the short-term outcomes of Tissue Engineered Decellularized Bovine pericardium (Synkroscaff®) in congenital heart surgery as a prosthetic material.

METHODOLOGY: This is a prospective observational cohort study. SynkroScaff® was used as prosthetic material in cohort of successive patients under 18 years of age requiring cardiac surgery for congenital heart diseases. Patients were evaluated for residual shunt, infective endocarditis, stenosis, calcification and aneurysmal dilatation at discharge, after 1 month, 3 months, 6 months and 1 year post-operatively.

RESULTS: Ninety-two patients were included, and the patch was used in ventricular septal defect (VSD), closure, aortic arch reconstructions and pulmonary arterioplasty (tetralogy of Fallot repair). Four (4.3%) had transient heart block, one had complete heart block needing a permanent pacemaker. A residual shunt was present in less than 5% of the VSD patients which spontaneously closed within 12 months. One patient of VSD repair had a significant residual shunt requiring redo surgery. The intra-operative ease of handling was rated as 9/9 in 92.3% of patients. None of the patients were noticed to develop patch leaks, aneurysmal dilatation or calcification on 12-month follow-up.

CONCLUSIONS: This tissue engineered bovine pericardium is a safe and reliable prosthetic material for corrective congenital heart surgery in short-term period.

PMID:39679085 | PMC:PMC11638438 | DOI:10.1007/s12055-024-01769-8

Surgical intervention of coronary-pulmonary artery fistula with multiple coronary aneurysms and Vieussens’ arterial ring formation

To our knowledge, there have been extremely few clinical reports on coronary-pulmonary artery fistula (CPAF) accompanied by coronary artery aneurysm (CAA) and Vieussens’ arterial ring (VAR), and few reports on…  Read More

Surgical intervention of coronary-pulmonary artery fistula with multiple coronary aneurysms and Vieussens’ arterial ring formation

To our knowledge, there have been extremely few clinical reports on coronary-pulmonary artery fistula (CPAF) accompanied by coronary artery aneurysm (CAA) and Vieussens’ arterial ring (VAR), and few reports on…  Read More

Tissue engineered decellularized bovine pericardium as prosthetic material in paediatric cardiac surgery

Indian J Thorac Cardiovasc Surg. 2025 Jan;41(1):35-40. doi: 10.1007/s12055-024-01769-8. Epub 2024 Jul 1.

ABSTRACT

AIM: To evaluate the short-term outcomes of Tissue Engineered Decellularized Bovine pericardium (Synkroscaff®) in congenital heart surgery as a prosthetic material.

METHODOLOGY: This is a prospective observational cohort study. SynkroScaff® was used as prosthetic material in cohort of successive patients under 18 years of age requiring cardiac surgery for congenital heart diseases. Patients were evaluated for residual shunt, infective endocarditis, stenosis, calcification and aneurysmal dilatation at discharge, after 1 month, 3 months, 6 months and 1 year post-operatively.

RESULTS: Ninety-two patients were included, and the patch was used in ventricular septal defect (VSD), closure, aortic arch reconstructions and pulmonary arterioplasty (tetralogy of Fallot repair). Four (4.3%) had transient heart block, one had complete heart block needing a permanent pacemaker. A residual shunt was present in less than 5% of the VSD patients which spontaneously closed within 12 months. One patient of VSD repair had a significant residual shunt requiring redo surgery. The intra-operative ease of handling was rated as 9/9 in 92.3% of patients. None of the patients were noticed to develop patch leaks, aneurysmal dilatation or calcification on 12-month follow-up.

CONCLUSIONS: This tissue engineered bovine pericardium is a safe and reliable prosthetic material for corrective congenital heart surgery in short-term period.

PMID:39679085 | PMC:PMC11638438 | DOI:10.1007/s12055-024-01769-8

Surgical intervention of coronary-pulmonary artery fistula with multiple coronary aneurysms and Vieussens’ arterial ring formation

To our knowledge, there have been extremely few clinical reports on coronary-pulmonary artery fistula (CPAF) accompanied by coronary artery aneurysm (CAA) and Vieussens’ arterial ring (VAR), and few reports on…  Read More

Surgical intervention of coronary-pulmonary artery fistula with multiple coronary aneurysms and Vieussens’ arterial ring formation

To our knowledge, there have been extremely few clinical reports on coronary-pulmonary artery fistula (CPAF) accompanied by coronary artery aneurysm (CAA) and Vieussens’ arterial ring (VAR), and few reports on…  Read More

Surgical intervention of coronary-pulmonary artery fistula with multiple coronary aneurysms and Vieussens’ arterial ring formation

To our knowledge, there have been extremely few clinical reports on coronary-pulmonary artery fistula (CPAF) accompanied by coronary artery aneurysm (CAA) and Vieussens’ arterial ring (VAR), and few reports on…  Read More

Management of a malignant solitary fibrous tumor of lung by uniportal video-assisted pneumonectomy: a case report

Solitary fibrous tumor (SFT) is a rare condition first described by Klemperer and Robin in 1931. Malignant SFTs account for approximately 80% of all SFT cases, and the five-year survival for malignant SFTs is …  Read More

Risk factors influencing the prognosis of patients with acute myocardial infarction and cardiogenic shock undergoing extracorporeal membrane oxygenation therapy

Patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) face high mortality rates. Extracorporeal Membrane Oxygenation (ECMO) therapy offers critical support in these cases, yet i…  Read More